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Fadlo R Khuri Selected Research

RSK inhibitor FMK

11/2013The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor metastasis.

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Fadlo R Khuri Research Topics

Disease

191Neoplasms (Cancer)
01/2022 - 01/2002
71Lung Neoplasms (Lung Cancer)
04/2021 - 01/2002
56Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2021 - 05/2002
39Squamous Cell Carcinoma of Head and Neck
01/2019 - 03/2002
24Head and Neck Neoplasms (Head and Neck Cancer)
11/2020 - 01/2004
13Carcinogenesis
11/2015 - 07/2002
11Neoplasm Metastasis (Metastasis)
01/2017 - 05/2003
6Small Cell Lung Carcinoma (Small Cell Lung Cancer)
12/2020 - 05/2012
6Neutropenia
08/2017 - 03/2002
5Multiple Myeloma
07/2015 - 12/2005
5Carcinoma (Carcinomatosis)
09/2009 - 07/2002
4Thyroid Neoplasms (Thyroid Cancer)
05/2022 - 01/2013
4Adenocarcinoma of Lung
11/2017 - 01/2008
4Colonic Neoplasms (Colon Cancer)
01/2017 - 12/2006
4Breast Neoplasms (Breast Cancer)
01/2016 - 10/2003
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/2014 - 01/2002
4Neurodegenerative Diseases (Neurodegenerative Disease)
10/2011 - 04/2006
4Fever (Fevers)
04/2010 - 03/2002
3Pain (Aches)
12/2020 - 12/2004
3Fatigue
12/2020 - 03/2004
3Melanoma (Melanoma, Malignant)
01/2018 - 01/2017
3Leukemia
09/2014 - 08/2014
3Hypoxia (Hypoxemia)
12/2011 - 04/2010
3Diarrhea
09/2011 - 05/2004

Drug/Important Bio-Agent (IBA)

32Proteins (Proteins, Gene)FDA Link
01/2022 - 08/2004
19ErbB Receptors (EGF Receptor)IBA
03/2016 - 05/2004
15Biomarkers (Surrogate Marker)IBA
11/2020 - 07/2003
15Biological ProductsIBA
01/2017 - 01/2002
14TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
12/2015 - 10/2004
13Erlotinib Hydrochloride (CP 358,774)FDA Link
07/2015 - 06/2004
13LigandsIBA
04/2013 - 01/2006
12EverolimusFDA Link
05/2022 - 08/2010
12Paclitaxel (Taxol)FDA LinkGeneric
04/2021 - 07/2002
12TOR Serine-Threonine KinasesIBA
12/2014 - 08/2005
12RetinoidsIBA
07/2012 - 02/2003
11Phosphotransferases (Kinase)IBA
07/2015 - 10/2004
11Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2014 - 05/2004
11Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2012 - 01/2006
10Cisplatin (Platino)FDA LinkGeneric
01/2019 - 01/2002
10Pharmaceutical PreparationsIBA
01/2017 - 01/2002
9Death Domain ReceptorsIBA
02/2021 - 12/2004
9Celecoxib (Celebrex)FDA Link
03/2014 - 12/2004
9Docetaxel (Taxotere)FDA Link
03/2013 - 03/2002
9lonafarnib (SCH 66336)IBA
09/2011 - 05/2004
9Isotretinoin (Accutane)FDA LinkGeneric
04/2007 - 01/2002
8EnzymesIBA
01/2018 - 10/2011
8Epidermal Growth Factor (EGF)IBA
12/2016 - 01/2009
7CurcuminIBA
01/2016 - 01/2007
7taxaneIBA
10/2015 - 05/2004
7Farnesyltranstransferase (Farnesyltransferase)IBA
06/2007 - 07/2002
6Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2018 - 12/2008
6Carboplatin (JM8)FDA LinkGeneric
08/2017 - 07/2002
6Small Interfering RNA (siRNA)IBA
05/2015 - 10/2007
6Sirolimus (Rapamycin)FDA Link
04/2015 - 08/2005
6Tyrosine Kinase InhibitorsIBA
04/2015 - 09/2008
6DNA (Deoxyribonucleic Acid)IBA
04/2015 - 10/2011
6Eukaryotic Initiation Factor-4EIBA
03/2013 - 11/2007
5MTOR InhibitorsIBA
02/2021 - 11/2007
5PlatinumIBA
01/2018 - 04/2009
5Caspase 8 (Caspase-8)IBA
12/2015 - 10/2007
5Proteasome InhibitorsIBA
07/2015 - 01/2006
5Tyrosine (L-Tyrosine)FDA Link
09/2014 - 11/2009
5Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
03/2011 - 06/2004
5Taxoids (Taxanes)IBA
04/2010 - 06/2002
5retinol palmitate (retinyl palmitate)FDA Link
02/2009 - 01/2002
5beta Carotene (Betacarotene)FDA Link
02/2009 - 01/2002
4Deoxyglucose (2 Deoxy D glucose)IBA
04/2021 - 04/2008
4RNA (Ribonucleic Acid)IBA
01/2021 - 04/2015
4Anaplastic Lymphoma KinaseIBA
03/2016 - 09/2012
4Messenger RNA (mRNA)IBA
10/2015 - 09/2002
4TubulinIBA
03/2014 - 01/2006
4SmokeIBA
03/2014 - 12/2004
4TransferasesIBA
09/2011 - 06/2004
4TeaIBA
06/2010 - 01/2007
4Bortezomib (Velcade)FDA Link
05/2010 - 01/2006
4bardoxolone methylIBA
09/2008 - 10/2004
4TriterpenesIBA
09/2008 - 10/2004
4alpha-TocopherolFDA Link
04/2007 - 07/2003
4Insulin-Like PeptidesIBA
10/2004 - 12/2002
4Insulin-Like Growth Factor Binding Protein 3IBA
10/2004 - 12/2002
3Monoclonal AntibodiesIBA
01/2018 - 04/2004
3human ERBB2 proteinIBA
11/2017 - 10/2015
3SeleniumIBA
11/2017 - 01/2005
3Cetuximab (Erbitux)FDA Link
02/2017 - 07/2014
3acetoacetic acid (acetoacetate)IBA
01/2017 - 08/2015
3Protein Isoforms (Isoforms)IBA
01/2017 - 01/2008
3CytokinesIBA
10/2015 - 05/2007
3Glucose (Dextrose)FDA LinkGeneric
08/2014 - 11/2009
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2014 - 05/2004
314-3-3 Proteins (14-3-3 Protein)IBA
05/2014 - 11/2008
3Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
03/2014 - 12/2004
3Carrier Proteins (Binding Protein)IBA
11/2013 - 04/2010
3Peptide Initiation Factors (Initiation Factor)IBA
03/2012 - 08/2009
3Tretinoin (Retinoic Acid)FDA LinkGeneric
08/2011 - 01/2002

Therapy/Procedure

67Therapeutics
12/2020 - 01/2002
27Drug Therapy (Chemotherapy)
08/2017 - 01/2002
25Chemoprevention
11/2020 - 01/2002
15Radiotherapy
12/2020 - 05/2002
5Induction Chemotherapy
09/2009 - 07/2002
3Salvage Therapy
12/2020 - 04/2010